Current Clinical Trials

Clinical trials are structured research studies in which participants volunteer to evaluate new treatments, interventions, or diagnostic approaches aimed at preventing, detecting, treating, or managing diseases and medical conditions. Some studies assess how individuals respond to a new intervention and monitor potential side effects, while others are designed to determine the most effective and appropriate dosing of a particular treatment.

A number of clinical trials are currently available in the United Kingdom and Ireland for the treatment of Immune Thrombocytopenia (ITP), with further details provided below. In addition, international trials are ongoing. A comprehensive and regularly updated listing can be accessed via ClinicalTrials.gov.

Study of Ianalumab in Adults With Primary Immune Thrombocytopenia (ITP) and Warm-antibody Autoimmune Hemolytic Anemia (wAIHA) Who Have Previously Benefited From Ianalumab (VAY RE-HIT).

Sponsor: Novartis Pharmaceuticals

Locations:

Imperial College, London W12 0HS – Recruiting

Link to Clincialtrials.gov page for this trial

A Study of Efgartigimod IV in Participants From 12 Years to Less Than 18 Years of Age With Chronic Immune Thrombocytopenia (ITP).

Sponsor: Argenx

Locations:

Cardiff, CF14 4XW – Recruiting

Link to Clincialtrials.gov page for this trial

A Follow-up Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia.

Sponsor: Takeda

Locations:

Barts Health NHS Trust, London, E1 1BB – Recruiting

University College London Hospitals, London, NW1 2PG

Imperial College NHS Trust, London, W12 OHS – Recruiting

University Hospitals of Leicester NHS Trust, LE1 5WW – Recruiting

Southampton General Hospital, SO16 6YD

Guys Hospital NHS Trust, SE1 9RT

Royal Liverpool and Broadgreen University Hospitals NHS Trust, L7 8XP

Greater Glasgow Health Board, G31 2ER

University Hospitals of North Midlands NHS Trust, Royal Stoke University Hospital, ST4 6QG

Leeds Teaching Hospitals NHS Trust, LS9 TF

Link to Clincialtrials.gov page for this trial

A Study of Mezagitamab in Adults With Chronic Primary Immune Thrombocytopenia.

Sponsor: Takeda

Locations:

Barts Health NHS Trust, London, E1 1BB – Recruiting

University College London Hospitals, London, NW1 2PG

Imperial College NHS Trust, London, W12 OHS – Recruiting

University Hospitals of Leicester NHS Trust, LE1 5WW – Recruiting

Southampton General Hospital, SO16 6YD – Recruiting

Guys Hospital NHS Trust, SE1 9RT – Recruiting

Royal Liverpool and Broadgreen University Hospitals NHS Trust, L7 8XP – Recruiting

Greater Glasgow Health Board, G31 2ER – Recruiting

University Hospitals of North Midlands NHS Trust, Royal Stoke University Hospital, ST4 6QG – Recruiting

Leeds Teaching Hospitals NHS Trust, LS9 TF – Recruiting

Link to Clincialtrials.gov page for this trial

A Study to Assess the Efficacy and Safety of Efgartigimod IV in Adult Participants With Primary Immune Thrombocytopenia (advance NEXT).

Sponsor: argenx

Locations:

Mater Misericordiae University Hospital, Dublin, Ireland, DO7 R2WY – Recruiting

St James’s Hospital – Cancer Clinical Trials Office, Dublin, Ireland, DO8 NHY1 – Recruiting

Queen Elizabeth Hospital Birmingham, B15 2GW – Recruiting

Bradford Teaching Hospitals NHS Foundation, BD9 6RJ – Recruiting

University Hospitals Coventry and Warwickshire NHS Trust, CV2 2DX – Recruiting

Glasgow Royal Infirmary – North Glasgow University Hospital Division, G4 0ET – Recruiting

University Hospitals of Leicester NHS Trust, LE1 5WW – Recruiting

Barts Health NHS Trust, London, E1 1BB – Recruiting

Imperial College NHS Trust, London, W12 OHS – Recruiting

Royal Cornwall Hospital (RCH), Truro, TR1 3LJ – Recruiting

Link to Clincialtrials.gov page for this trial

A Study of Pirtobrutinib in Participants With Immune Thrombocytopenia.

Sponsor: Eli Lilly and Company

Bristol Haematology and Oncology Centre, BS2 8ED – Recruiting

St James’s University Hospital, Leeds, LS9 7TF – Recruiting

Leicester Royal Infirmary, LE1 5WW – Recruiting

Royal London Hospital, , E1 1FR

Imperial College, London, W12 0HS

Link to Clincialtrials.gov page for this trial